Oncogenic Serine/Threonine Kinase Aurora 2

Cartoons view of Aurora-2 from Homo sapiens

View of the active site of Aurora Kinase 2. Residues 279-292 were disordered on the electron densit map and do not appear in the final structure.

View of the ATP binding pocket (red) bound to ATP yellow.

Cheetham, G.M.T., Knegtel, R.M.A., Coll, J.T., Renwick, S.B., Swenson, L., Weber, P., Lippke, J.A., Austen, D.A. Crystal structure of aurora-2, an oncogenic serine/threonine kinase. J.Biol.Chem. v277 pp.42419-42422 , 2002 (PubMed)

1MUO(PDB)