BIOL 6312
HOMEWORK
due 24 February 2003

1. Identify a protein whose structure has been determined in the past year or so.
Go to the library and scan issues of Science, Nature or Journal of Molecular Biology (or other journals) from 2001-2003. Or you can scan Tables of Contents of various journals online, using the links on my webpage. Find a protein whose structure is described in a full length article, not a note (2-3 pages).

2. Summarize the secondary structure and tertiary organization (the fold) of the protein.
Confine your description to one page. Include estimates of the number of elements of alpha helix, beta sheet, etc. Also identify motifs that are present, and the overall organization. Treat each domain separately, if there are more than one. Identify the location of the active site, if there is one. Provide a reference to the paper.

3. In class on Monday February 24 each student will give a 5-10 minute report to the class summarizing the structure of his or her protein. Does the protein fit into the families we have discussed? You may use up to 3 transparencies or figures. Power point is OK. See me if you have any questions.