Dimeric Human Prp A dimeric human Prp is domain-swapped. Interestingly, this also requires disulfide swapping (cysteines in red). Knaus KJ, Morillas M, Swietnicki W, Malone M, Surewicz WK, Yee VC. Related Articles, Links Crystal structure of the human prion protein reveals a mechanism for oligomerization. Nat Struct Biol. 2001 Sep;8(9):770-4. (PubMed) 1i4m (PDB)