| Contributions to specificity and affinity
Oleate is bound to a lipid-binding protein. Its carbon atoms are colored yellow. Two nonpolar interactions, contributing to affinity are shown with a Val and a Phe. Hydrogen bonding is shown with a water molecule and a Tyr. This contributes to specificity. Xu, Z., Bernlohr, D. A., Banaszak, L. J.: The adipocyte lipid-binding protein at 1.6-A resolution. Crystal structures of the apoprotein and with bound saturated and unsaturated fatty acids. J Biol Chem 268 pp. 7874 (1993) 1lid (PDB) |