Alpha/Beta Barrel: Triosephosphate isomerase

Banner, D. W., Bloomer, A. C., Petsko, G. A., Phillips, D. C., Wilson, I. A.: Atomic coordinates for triose phosphate isomerase from chicken muscle. Biochem Biophys Res Commun 72 pp. 146 (1976) (PubMed)

1tim (PDB)

		Cartoons view of Triosephosphate isomerase, an 8-stranded alpha/beta barrel protein. The center contains an 8-stranded parallel beta-sheet. Each adjacent pair of beta-strands is connected by an alpha helix, making the outer surface of the protein.
		The beta-alpha-beta motif is highlighted: beta strands in blue, alpha helix in green. It has right-handed connectivity.
		In alpha/beta barrel proteins, the active site is typically formed from the loops at the C-terminal ends of the parallel beta-strands. These are colored yellow, in spacefilling.