Grants Received     

 

Petroleum Research Fund "A Stereospecific Synthesis of the Olivanic Acids MM22380 and MM22382 (1982-1984, $10,000).

Robert A. Welch Foundation "The Total Synthesis of the Carbapenem Antibiotics" (1982-1985, $54,000).

Research Corporation "(Silylamino)phosphines as Useful Reagents in Mechanistic and Synthetic Organic Chemistry", (1983-1985, $7,800).

Robert A. Welch Foundation "Applications of Allenes in Organic Synthesis" (1985-1988, $60,000).

Petroleum Research Fund "The Use of Substituted Allenes in the Synthesis of b-Lactam Antibiotics"  (1985-1987, $15,000).

Petroleum Research Fund "The Preparation of a-Vinylidene-b-lactam Antibiotics" (Summer Research Fellowship, 1987, $2,000).

Robert A. Welch Foundation Supplement "The Use of Substituted Allenes in the Synthesis of b-Lactam Antibiotics" (1987, $5,000).

Petroleum Research Fund Seed Grant (1987, $1,000).

National Institute of Health "Synthetic Applications of Allenes in Organic Chemistry" (1986-1989, $134,407).

Petroleum Research Fund "The Thermal Rearrangement of  a-Substituted Silanes:  Stereochemistry and Synthetic Utility" (1987-1989, $20,000).

National Institute of Health "The Thermal Rearrangement of a-Substituted Silanes:  Stereochemistry and Synthetic Utility"(1987-1990, $169,043).  Received priority score of 125 (top 2% of applicants nationwide).

Robert A. Welch Foundation "Rearrangements of Functionalized Organosilanes" (1988-1991, $75,000).

American Cyanamid "Synthesis of Novel Antibiotics" (1988-1990, $84,000)

Petroleum Research Fund "Penam and Cephem-Derived Enzyme Inhibitors" (1990 - 1992, $20,000).

American Cyanamid "Synthesis of Novel Antibiotics" (1990-1991, $42,000).

National Institute of Health "Allenes of Synthetic and Biochemical Importance"  (1991-1995, $247,000).

Robert A. Welch Foundation "Rearrangements of Functionalized Organosilanes" (1991-1994, $90,000).

Robert A. Welch Foundation "New Applications for Organosilicon Chemistry" (1994-1997, $96,000).

National Institute of Health " Calcium Pathways in African Trypanosomes" 1994-1997, $348,000.  (Co-investigator with Larry Ruben).  

Petroleum Research Fund "Synthesis and Biological Evaluation of b-Lactamase Substrates and Inhibitors" (1995-1997, $25,000).

SMU President’s Partners Grant, “Science at the Frontiers of Biology, Chemistry, and Medicine: Molecular Modeling Software” (1996-7, $2,500).

Robert A. Welch Foundation "Rational and Combinatorial Approaches to Protease Inhibition" (1997-2000, $111,000).

Petroleum Research Fund  "Inhibitors of b-Lactamase and HLE: Modeling, Synthetic, and Crystallographic Studies" (1998-2000, $30,000).

Research Corporation Technologies “A Study of the Antimicrobial Activity of Novel b-Lactamase Inhibitors” (2000-2001, $78, 026).

Texas Higher Education Coordinating Board (Advanced Technology Proposal) “Bifunctional b-Lactamase Inhibitors to Simultanteously Target Serine and Metallolactamases” (2000-2002, $102,594).

Robert A. Welch Foundation "Rational and Combinatorial Approaches to Protease Inhibition" (2000-2002, $129,000).

Petroleum Research Fund  “New Methodology for the Synthesis of Functionalized Cephalosporins” (2001-2003, $30,000).

National Institute of Health  “Broad Spectrum b-Lactamase Inhibitors” (2001-2002, $160,232).

Robert A. Welch Foundation (2003-2006, $150,000).

Centers for Disease Control "Library Design Targeted at Resistant Baceria" ($289,000, 2004-2005).

National Institute of Health "Dual Purpose b-Lactamase Inhibitors"  ($133,820, 2004-2005).

Becton Dickinson Diagnostics "Diagnostic b-Lactamase Inhibitors" ($22,553, 2004-2005)

AlamX LLC, "Antimicrobial Effects of Synergistic Combinations" ($50,000, 2004-2005)

Robert A. Welch Foundation ³Rational and Combinatorial Approaches to Protease Inhibition² (2006-2009, $150,000)

 

 

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