Eva Oberdörster, Ph.D.
Senior Lecturer
Department of Biology
T: 214-768-1241
Courses: (Fall 2007 hyperlinked)
Biology 1303: Essentials of Biology
Biology 1310: Aquatic Biology of the Southwest
Biology 1402: Introductory Biology
Biology 3306: Physiology and Regulatory Biology
Biology 4132: Senior Seminar on Nanotechnology
Biology 4160: Toxicology Laboratory
Biology 4360: Environmental and Human Toxicology
Biology 5110: Biochemistry Laboratory
MAJOR RESEARCH INTERESTS
1. What is the mechanism of nanoparticle toxicity?
Please see also more information on my NanoTox web site.
2. What types of cell-signaling pathways are used by invertebrate peptide and steroid hormones?
3. What are the impacts on the environment from Concentrated Animal Feedlot Operations (CAFOs)?
For more information about steroids in the environment, please see a recent Science News article by Janet Raloff on the topic.
For more information on endocrine disruption, please see:
the e.hormone web page
We were recently visited by Dr. Lou Guillette who gave a seminar on "Contaminants as hormones: Lessons from the swamp". The question/answer session went well into the reception. Two of my students, Traci Jones and Shilpa Gandhi, joined us for dinner and chatted about Life, careers, and science. A link to Lou's web site.
The seminar Lou chats with Paulencia Morris, a student in Biochemistry
For more information in invertebrate endocrine disruption, please see:
http://kintyre.st-andrews.ac.uk/sites/flycell/index.html
EDUCATION
May 1992 B.S. Biology (Major), Anthropology (Minor)
Binghamton University, Binghamton, NY
May 1997 Ph.D. Zoology; Integrated Toxicology Program
Duke University, Durham, NC. Dr. Dan Rittschof, Dissertation Advisor
PREVIOUS POSITIONS HELD
1997-1998 Post-Doctoral Fellow, Tulane/Xavier Center for Bioenvironmental
Research
Tulane University, New Orleans, LA. Dr. J. A. McLachlan, Advisor
1998-2000 Assistant Professor of Biochemical Ecotoxicology and Molecular
Toxicology
Clemson University, Department of Environmental Toxicology, Clemson, SC.
PROFESSIONAL SOCIETIES
Society of Environmental Toxicology and Aquatic Chemistry (SETAC) since 1996
Society of Toxicology (SOT) since 1998, Vice President of the Women in Toxicology (WIT) Specialty Section
American Association of Zoos and Aquaria (AZA) since 2000
RECENT GRANTS
2002 US EPA, Region 6 ($170,000, 3 years)
Co-PI with Dr. John Easton, SMU Environmental Engineering
Environmental levels and toxicity of ED hormones released from concentrated animal
feeding operations and sanitary sewer overflows in the Bosque River, TX.
2002 US Fish and Wildlife Service, open-ended contract
Analysis of fish from Arkansas Wildlife Refuges for elevated liver EROD activity.
SELECTED PEER-REVIEWED PUBLICATIONS
Oberdörster E, D Rittschof, P McClellan-Green. 1998. Induction of Cytochrome P450 3A and heat shock protein by tributyltin in blue crab, Callinectes sapidus. Aquat. Toxicol. 41:83-100.
Oberdörster E, D Rittschof, GA LeBlanc. 1998. Alteration of [14C]-Testosterone metabolism after chronic tributyltin exposure in Daphnia magna. Arch. Environ. Contam. Toxicol. 34:21-25.
Oberdörster E, D Rittschof, and P McClellan-Green. 1998. Testosterone metabolism in imposex and normal I. obsoleta: Studies with field collected and TBT Cl-induced imposex snails. Mar. Poll. Bull. 36:144-151.
Cheek AO, P Vonier, BC Burow, E Oberdörster, JA McLachlan. 1998. Environmental Signaling: A biological context for endocrine disruption. Environ. Health Persp. 106, Suppl. 1:5-10.
Oberdörster E, M Martin, CF Ide, JA McLachlan. 1999. Benthic community structure and biomarker induction in grass shrimp in an estuarine system. Arch. Environ. Contam. Toxicol. 37(4):512-518.
Oberdörster E, DM Cottam, FA Wilmot, MJ Milner, JA McLachlan. 1999. Interaction of PAHs and PCBs with ecdysone-dependent gene expression and cell proliferation. Tox. Appl. Pharm. 160(1):101-108.
Ingersoll CG, M Crane, S Dodson, T De Witt, A Gies, M-C Huet, T Hutchinson, C McKenney, E Oberdörster, D Pascoe, DJ Versteeg, O Warwick. 1999. Chapter 3: Laboratory toxicity tests for use in evaluating potential effects of endocrine disrupting compounds (EDCs). In: Endocrine Disruption in Invertebrates: Endocrinology, Testing and Assessment. SETAC Press, Pensacola, FL. pp. 107-197.
Oberdörster E, M Brouwer, T Hoexum-Brouwer, S Manning and JA McLachlan. 2000. Long-term pyrene exposure of grass shrimp, Palaemonetes pugio, affects molting and reproduction of males and offspring of exposed females. Environ. Health Persp. 108(7):641-646.
Oberdörster E, LK Irwin and CD Rice. 2000. Purification of lipovitellin from grass shrimp Palaemonetes pugio, generation and characterization of monoclonal antibodies, and validation for the detection of lipovitellin in Crustacea. Comp. Biochem. Physiol. 127C(2):199-207.
Oberdörster E, P McClellan-Green. 2000. The neuropeptide APGWamide induces imposex in the mud snail Ilyanassa obsoleta. Peptides. 21(9):1323-1330.
Oberdörster E, AO Cheek. 2001. Gender Benders at the Beach: Endocrine Disruption in Marine and Estuarine Organisms. Environ. Contam. Toxicol. 20(1):23-36.
Oberdörster E, MA Clay, DM Cottam, FA Wilmot, MJ Milner and JA McLachlan. 2001. Common phytochemicals are Ecdysteroid agonists and antagonists: A possible evolutionary link between vertebrate and invertebrate steroid hormones. J. Steroid Biochem. Molec. Biol. 77(4-5):229-38.
Irwin, LK, SL Gray, E Oberdörster. 2001. Vitellogenin induction in painted turtle, Chrysemys picta, as a biomarker of exposure to environmental levels of estradiol. Aquat. Toxicol. 55:49-60.
Oberdörster E. 2001. Peptide hormones vs. Steroid hormones: Case studies from snail and turtle populations. Annals of the New York Academy of Sciences. Special Issue: Environmental Hormones: The Scientific Basis of Endocrine Disruption. 948:75-79
Oberdörster E
, P McClellan-Green. 2002. Mechanisms of imposex induction in mud snail, Ilyanassa obsoleta: TBT as a neurotoxin and aromatase inhibitor. Marine Environmental Research. 54(3-5) p. 715-718.
Oberdörster E. (2004) Manufactured nanomaterials (Fullerenes, C60) induce oxidative stress in brain of juvenile largemouth bass. Environmental Health Perspectives. (available on-line)
Gunderson MP, Oberdörster E, Guillette LJ Jr. 2004. Phase I and phase II hepatic enzyme activities in juvenile alligators collected from three sites in the Kissimmee-Everglades drainage, Florida. Comp Biochem Physiol. 139C:39-46.
Oberdörster, E, J. Romano, P. McClellan-Green. The neuropeptide hormone APGWamide as a Penis Morphogenic Factor (PMF) in gastropod mollusks. 46: In Press.
Oberdörster, G, E. Oberdörster, J. Oberdoerster. Nanotoxicology: An Emerging Discipline Evolving from Studies of Ultrafine Particulates. Environmental Health Perspectives. (available on-line)
McClellan-Green, P., J. Romano and E. Oberdörster. Does gender really matter in contaminant exposure? A case study using Invertebrate Models. JRC. In Press.
Haasch, M.L., P. McClellan-Green, and E. Oberdörster. Consideration of the toxicity of nanoparticles. American Institute of Physics. In Press.
Zhu, S., E. Oberdörster, and M. L. Haasch. Toxicity of an engineered nanoparticle (fullerene) in two aquatic species, daphnia and fathead minnow. Mar Env Res. In press.
Oberdörster, E., P.McClellan-Green, and M.L. Haasch. 2005. Ecotoxicity of Engineered Nanomaterials. Wiley-VCH Book Series on Nanotechnology for Life Sciences - Vol 5, In Press.
E. Oberdörster, P. McClellan-Green, Zhu, S., and M. L. Haasch. Toxicity of fullerene and single-walled carbon nanotubes in environmentally relevant species. Carbon. In Press.
Gunderson, MP, E Oberdörster, B North, LJ Guillette, Jr. In preparation. A one-time low-dose of ethanol during development alters liver enzyme activities in juvenile alligators.
Gravel, P, KM Johanning, J Vargas, JA McLachlan and E. Oberdörster. Imposex in Costa Rican waters in Acanthais brevidentata. Accepted, in revision.
Dr. Oberdörster (elder); Dr. J. Oberdoerster, and Dr. E. Oberdörster at SOT 2003
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