Clockwise, starting
at top-left: Hongmei Li, Debashish Roy, Andrew Vogt, Ming Li,
Jennifer Cambre, Abhijeet Bapat, Sara Gingrich, Aman Ullah,
Priydarsi De (group alumnus), Young-Hoon Lim
Address: Department of Chemistry Southern Methodist University PO Box 750314 Dallas, TX 75275-0314 PH: (214) 768-8802 Email:-bsumerlin@smu.edu-
Postdoctoral
Research Associates
Dr. Debashish Roy
Education: Ph. D., Polymer
Chemistry, University of Leeds, Leeds, UK, 2007 Advisor: Dr. Sébastien
Perrier
M.Sc., Design & Manufacture, De Montfort University, Leicester,
UK, 2003
B.Sc., Leather Technology, University of Dhaka, Dhaka,
Bangladesh, 1998
Current Research Project and objectives:
Roy’s primary research project involves an investigation towards
the syntheses and applications of advanced macromolecular
architectures based on boronic acid-containing polymers. In
addition to homopolymers and block copolymers being prepared via
reversible addition-fragmentation chain transfer (RAFT)
polymerization and atom transfer radical polymerization (ATRP),
basic organic and inorganic synthetic techniques are employed to
prepare novel, reversible and responsive polymeric systems.
Selected Publications:
Priyadarsi De, Sudershan R. Gondi,
Debashish Roy, Brent S. Sumerlin "Boronic Acid Terminated
Polymers: Synthesis by RAFT and Subsequent Dynamic Covalent
Self-Assembly" Macromolecules2009, 42,
5614–5621.
http://dx.doi.org/10.1021/ma900835y Free link: [Link]
Debashish Roy, Jennifer N. Cambre, Brent
S. Sumerlin "Triply-responsive boronic acid block
copolymers: Solution self-assembly induced by changes in
temperature, pH, or sugar concentration" Chemical
Communications2009, 2106-2108.
http://dx.doi.org/10.1039/B900374F
Jennifer N. Cambre, Debashish
Roy, Sudershan R. Gondi, Brent S. Sumerlin "Facile Strategy to
Well-Defined Water-Soluble Boronic Acid (Co)polymers"Journal of the
American Chemical Society2007, 129, 10348-10349.
http://dx.doi.org/10.1021/ja074239s
Debashish Roy,
James T. Guthrie and Sébastien Perrier, Graft Polymerization:Grafting polystyrene from
Cellulose via Reversible Addition-Fragmentation Chain Transfer
(RAFT) Polymerization Macromolecules2005, 38,
10363.
Debashish Roy, James T.
Guthrie and Sébastien Perrier, Reversible
Addition-Fragmentation Chain Transfer (RAFT) Graft
Polymerization of 2-(Dimethylaminoethyl) methacrylate onto
Cellulose FiberAustralian Journal of Chemistry
2006, 59, 737.
Debashish Roy,
Controlled Modification of Cellulosic Surfaces via the
Reversible Addition-Fragmentation Chain Transfer (RAFT)
Polymerization ProcessAustralian Journal of Chemistry2006, 59, 229.
Sébastien
Perrier, Pittaya Takolpuckdee, Steven Brown, Thomas M. Legge,
Debashish Roy, Murray R. Wood, Steven P. Rannard, and David
J. Duncalf, Progress in RAFT/MADIX Polymerization. Synthesis,
Use, and Recovery of Chain Transfer Agents, ACS Symposium
Series, Controlled/Living Radical Polymerization-From Synthesis
to Materials, (Matyjaszewski, K., Ed.) 2006, 30,
438.
Address: Department of Chemistry Southern Methodist University PO Box 750314 Dallas, TX 75275-0314 PH: (214) 768-7879 Email:droy@smu.edu
Graduate Students
Jennifer N. Cambre
Education:
Ph.D.
Candidate, Chemistry, Southern Methodist University Advisor: Dr. Brent S. Sumerlin
M.S.,
Chemistry, Southern Methodist University, 2003
Research Synopsis: Synthesis and characterization of
inorganic-organic graft copolymers using atom transfer radical
polymerization (ATRP) Advisor: Dr. Patty Wisian-Neilson
Current
Research Projects and Objectives:
Polymers with amphiphilicity and stimuli-responsive behavior are
a type of “smart” materials known as double hydrophilic block
copolymers. These polymers are generally composed of AB diblock
copolymers in which one block (A) is hydrophilic and the other
(B) can be hydrophobic or hydrophilic depending on the
conditions of the surrounding environment. When an appropriate
stimulus is applied to the system, multimolecular structures
arise with the B block forming the hydrophobic core. Micelle or
vesicle formation can be induced by changes in pH, temperature,
light, or specific small molecule organics.
Publications: Debashish Roy, Jennifer N. Cambre, Brent
S. Sumerlin "Triply-responsive boronic acid block
copolymers: Solution self-assembly induced by changes in
temperature, pH, or sugar concentration" Chemical
Communications2009, In press.
http://dx.doi.org/10.1039/B900374F
Jennifer N. Cambre, Debashish
Roy, Sudershan R. Gondi, Brent S. Sumerlin "Facile Strategy to
Well-Defined Water-Soluble Boronic Acid (Co)polymers"Journal of the
American Chemical Society2007, 129, 10348-10349.
http://dx.doi.org/10.1021/ja074239s
Jennifer N. Cambre, Patty Wisian-Neilson “Poly(methylphenylphosphazene)-Graft-Poly(methyl
methacrylate) Copolymers Via Atom Transfer Radical
Polymerization”J. Inorg. Organomet. Polym. Mater. 2006, 16, 311-318.
Jennifer N.
Cambre, Patty Wisian-Neilson “ATRP Grafting Reactions on
Poly(methylphenylphosphazene)”Polymer Preprints
2003, 44(1), 919-920.
Address: Department of Chemistry Southern Methodist University PO Box 750314 Dallas, TX 75275-0314 PH: (214) 768-7879 Email:
-jcambre@smu.edu-
B.Tech. Chemical Technology, Laxminarayan
Institute of Technology, Nagpur University, Maharashtra, India
(2003).
Current
Research Projects and Objectives:
Responsive block copolymers and novel thermoplastic elastomers
are being prepared by RAFT polymerization of monomers derived
from renewable resources. It is our goal to exploit alternative
resources for the preparation of materials that are typically
derived from petroleum-based compounds. To further minimize the
potential collateral impact of precise polymer synthesis,
microwave irradiation is being investigated as an
energy-efficient pathway to well-defined block copolymers.
Address: Department of Chemistry Southern Methodist University PO Box 750314 Dallas, TX 75275-0314 PH: (214) 768-7879 Email:-abapat@smu.edu-
Hongmei Li
Education:
Ph.D. Candidate, Chemistry, Southern Methodist University Advisor: Dr. Brent S. Sumerlin
M.S.,
Biochemistry and Molecular Biology, Jilin University, Changchun,
China, 2003 Thesis topic: Study on Short Peptide Ligands Binding with
Insulin Receptor and Quantum Dot Labeling Advisor:
Dr. Wei Li
B.S.,
Biotechnology, Jilin University, Changchun, China, 1999 Research synopsis: Synthesis of
selenium-dibridged-6,6’-4,4’-β-cyclodextrin conjugate that acted
as a glutathione peroxidase mimic.
Advisor: Dr. Guimin Luo
Current Research Projects and Objectives: We are
employing RAFT polymerization to prepare
stimuli-responsive polymer-protein bioconjugates with particular
focus on the modification of proteins capable of serving as
biocatalysts. By modulating the size and solubility of the
conjugated polymer, it is possible to tune the activity and
recyclability of the enzyme to which it is attached.
Publications: Hongmei
Li, Dunming Zhu, Brooke A.Hyatt, Fahad M. Malik, Edward R. Biehl
and Ling Hua “Cloning,
Protein Sequence Clarification, and Substrate Specificity of a
Leucine Dehydrogenase from Bacillus sphaericus ATCC4525”Appl. Biochem. Biotechnol.2008,
158, 343-351.
http://dx.doi.org/10.1007/s12010-008-8304-2
Address: Department of Chemistry Southern Methodist University PO Box 750314 Dallas, TX 75275-0314 Email: -hongmeil@smu.edu
Ming Li
Education:
Ph.D. Candidate, Chemistry, Southern Methodist University Advisor: Dr. Brent S. Sumerlin
M.S.,
Materials Science, Shanghai Jiao Tong University (Shanghai),
2005 Thesis topic: Functionalization of hyperbranched polymers Advisor: Xinling Wang
Current Research Projects and Objectives: We
employ controlled polymerization techniques such as atom
transfer radical polymerization (ATRP) and reversible
addition-fragmentation chain transfer (RAFT) to prepare
stimuli-responsive polymer-protein bioconjugates. In addition to
considering the potential of these natural-synthetic hybrids for
therapeutic applications, we also are interested in the
fundamental solution behavior that arises upon the application
of an appropriate stimulus.
Publications: Priyadarsi De, Ming Li, Sudershan R.
Gondi, Brent S. Sumerlin "Temperature-Regulated Activity of
Responsive Polymer-Protein Conjugates Prepared by Grafting-from
via RAFT Polymerization"Journal of the American Chemical
Society 2008, In press.
http://dx.doi.org/10.1021/ja804495v
Ming Li, Priyadarsi De, Sudershan R. Gondi, Brent S. Sumerlin
“End Group Transformations of RAFT-Generated Polymers with
Bismaleimides: Functional Telechelics and Modular Block Copolymers”J. Polym. Sci. Part A: Polym. Chem. 2008, 46,
5093-5100.
http://dx.doi.org/10.1002/pola.22837
Ming Li, Priyadarsi De, Sudershan R.
Gondi, Brent S. Sumerlin "Responsive Polymer-Protein
Bioconjugates Prepared by RAFT Polymerization and
Copper-Catalyzed Azide-Alkyne Click Chemistry"
Macromolecular Rapid Communications 2008, 29,
1172-1176.
http://dx.doi.org/10.1002/marc.200800073
Highlighted in the
June 2008 edition of
Materials View.
Ming Li, Xiaohui Yang, Yunhang Liu, Xinling Wang “Synthesis
and Characterization of New Hyperbranched Polymers with Only
Inner Functional Groups Modified” J. Appl. Polym. Sci.2006, 101, 317–322
Address: Department of Chemistry Southern Methodist University PO Box 750314 Dallas, TX 75275-0314 PH: (214) 768-7879 Email: -mingl@mail.smu.edu-
Aman Ullah
(visiting student)
Education: Ph.D. Candidate, Department of Chemistry & Industrial
Chemistry, University of Genova, Italy. Advisor: Prof. Saverio Russo & Co-advisor: Dr. Orietta Monticelli
M.Sc. Organic Chemistry
University of Agriculture Faisalabad Pakistan, 2002
B.Sc. Chemistry, University of
Panjab Lahore Pakistan, 2000
Current Research Projects and Objectives:
We are currently investigating RAFT polymerization of various
monomers under microwave conditions. An unfortunate consequence
of the control provided by RAFT is that the polymerizations are
often significantly slower than analogous conventional radical
polymerizations. Therefore, we are investigating the application
of microwave reaction conditions to facilitate higher
polymerization rates. As compared to those exposed to
conventional heating, microwave-assisted reactions are
dramatically faster and hold great promise for the industrial
application of RAFT chemistry.
Publications:
Aman Ullah, A. Jabbar, T.M. Babar, H. Mahmood, R. Ahmad and A.
Khan "Proximate Analysis of Celestite Ore of Khairabad (Daud
Khail)"Pak. J. Nat. Science. 2004, 2,
67-74.
N. Tahir,
Aman Ullah, A. Jabbar, A. A. Chattha, H. Mahmood, T. M. Babar &
Ahmad "Pilot scale production of barium meal/ BaSO4 from
Indigenous barite ore"Pak. J. Nat. Sci.2004,
2, 35-40.
Nasir
Rasool, Viqar uddin Ahmad, Naseem Shahzad, Muhammad Abid Rashid,
Aman Ullah, Zahid Hassan, Muhammad Zubair, and Rasool Bakhsh
Tareen "New ent-Kaurane type diterpene glycoside, Pulcaroside-B,
from Pulicaria undulata"Nat. Prod. Commun.2008, 2, 141-144
Address: Department of Chemistry Southern Methodist University PO Box 750314 Dallas, TX 75275-0314 PH: (214) 768-7879 Email: -aullah@smu.edu-
Xiao Yu
Education: Ph.D. Candidate,
Chemistry, Southern Methodist University Advisor: Dr. Brent S. Sumerlin
B.S.,Polymer Science and
Engineering, Beijing University of Chemical Technology (BUCT),
Beijing, China,2004-2008
Current Research Projects and Objectives:
By
employing polymeric species which exhibit a responsive behavior
to an environmental change (temperature, wavelength of light,
pH, etc.) along with these selective, controlled processes, we
are able to create specifically designed macromolecular
structures with designated therapeutic potentials. Such
examples are the controlled release of a particular drug
dependent, yet counteractive, on the environmental concentration
rise of a certain chemical, or the potential of new scaffolding
materials for bone growth or tissue regeneration. Our
research helps to create and define the parameters or limits in
which these new “smart” materials can be created.
Address: Department of Chemistry Southern Methodist University PO Box 750314 Dallas, TX 75275-0314 PH: (214) 768-7879 Email: -drewpvogt@gmail.com-
Undergraduate Students
Sara J. Gingrich
Education: B.S. Candidate,
Southern Methodist University Advisor: Dr. Brent S. Sumerlin
Young Hoon Lim
Education: B.S. Candidate,
Southern Methodist University Advisor: Dr. Brent S. Sumerlin
Alumni
Graduate Students
Dr. Andrew P. Vogt
(Flinders University, Adelaide, AU)
