The Lippert Research Group

Publications Affiliated with SMU:
  1. An, W.; Mason, R. P.; Lippert, A. R. "Energy Transfer Chemiluminescence for Ratiometric pH Imaging." Org. Biomol. Chem. 2018, Accepted Manuscript. doi:10.1039/C8OB00972D


  2. Cao, J.; An, W.; Reeves, A. G.; Lippert, A. R. "A Chemiluminescent Probe for Cellular Peroxynitrite Using a Self-Immolative Oxidative Decarbonylation Reaction." Chem. Sci. 2018, 9, 2552-2558. doi:10.1002/anie.201711228


  3. Ryan, L. S; Lippert, A. R. "Ultrasensitive Chemiluminescent Detection of Cathepsin B: Insights into the New Frontier of Chemiluminescent Imaging." Angew. Chem. 2018, 57, 622-624. doi:10.1002/anie.201711228 (Highlight Article)

  4. Patel, S. K.; Cao, J.; Lippert, A. R. "A Volumetric Digital Light 3D Photoactivatable Dye Display." Nature Commun. 2017, 15239. doi:10.1039/C7AY01238A [SMU Research] [EurekAlert!] [Phys.Org] [NovusLight] [Optics & Photonics News] [Cosmos Magazine] [Digital Trends]


  5. Kroll, J. L.; Werchan, C. A.; Reeves, A. G.; Bruemmer, K. J.; Lippert, A. R.; Ritz, T. "Sensitivity of salivary hydrogen sulfide to psychological stress and its association with exhaled nitric oxide and affect." Physiol. Behav. 2017, 179, 99-104. doi:10.1016/j.physbeh.2017.05.023


  6. Reeves, A. G.; Subbarao, M.; Lippert, A. R. "Imaging acetaldehyde formation during ethanol metabolism in living cells using a hydrazine naphthalimide fluorescent probe." Anal. Methods 2017, 9, 3418-3421. doi:10.1039/C7AY01238A


  7. Lippert, A. R. "Unlocking the Potential of Chemiluminescence Imaging." ACS Cent. Sci. 2017 3, 269-271. doi:10.1021/acscentsci.7b00107 (First Reactions)


  8. Lippert, A. R.*; Cao, J. "1-(Cyanomethyl)tetrahydro-1H-thiophen-1-ium Bromide." e-EROS Encyclopedia of Reagents for Organic Synthesis 2016 1-4. doi:10.1002/047084289X.rn01962


  9. Quimbar, M.E.; Krenek, K. M.; Lippert, A. R.* "A chemiluminescent platform for smartphone monitoring of H2O2 in human exhaled breath condensates." Methods 2016, 109, 123. doi:10.1016/j.ymeth.2016.05.017

    TOC Graphic Smartphone.jpg

  10. Cao, J.; Campbell, J.; Liu, L.; Mason, R. P.; Lippert, A. R.* "In Vivo Chemiluminescent Imaging Agents for Nitroreductase and Tissue Oxygenation." Anal. Chem. 2016, 88, 4995. doi:10.1021/acs.analchem.6b01096

    TOC Graphic CHS3.jpg

  11. Cao, J.; Lopez, R.; Thacker J. M.; Moon, J. Y.; Jiang, C.; Morris, S. N. S.; Bauer, J. H.; Tao, P.; Mason, R. P.; Lippert, A. R.* "Chemiluminescent Probes for Imaging H2S in Living Animals." Chem. Sci. 2015, 6, 1979. doi: 10.1039/C4SC03516J.

    TOC Graphic CHS3.jpg

  12. Lin, V. S.; Lippert, A. R.*; Chang, C. J.* "Azide-Based Fluoresent Probes: Imaging Hydrogen Sulfide in Living Systems." Methods Enzymol. 2015, 1264, 231. doi: 10.1016/bs.mie.2014.11.011.


  13. Lippert, A. R.*; Dickinson, B. C.; New, E. J. "Chapter 21: Imaging Mitchondrial Hydrogen Peroxide in Living Cells." Methods Mol. Biol. 2015, 554, 63. doi: 10.1007/978-1-4939-2257-4_21.


  14. Bruemmer, K. J.; Merrikhihaghi, S.; Lollar, C. T.; Morris, S. N. S.; Bauer, J. H.; Lippert, A. R.* "19F Magnetic Resonance Probes for Detecting Peroxynitrite in Living Cells Using an Oxidative Decarbonylation Reaction." Chem. Commun. 2014, 50, 12311. doi: 10.1039/C4CC04292A

    5-fluoroisatin is now commercially available from Sigma-Aldrich!


  15. Lippert, A. R.* "Designing Reaction-Based Fluorescent Probes for Selective Hydrogen Sulfide Detection." J. Inorg. Biochem. 2014, 133, 136. doi: 10.1016/j.jinorgbio.2013.10.010


  16. Lollar, C. T.; Krenek, K. M.; Bruemmer, K.J.; Lippert, A. R.* "Ylide Mediated Carbonyl Homologations for the Preparation of Isatin Derivatives." Org. Biomol. Chem. 2014, 12, 406. doi: 10.1039/C3OB42024H.


  17. Lin, V. S.; Lippert, A. R.; Chang, C. J.* "Cell-trappable fluorescent probes for endogenous hydrogen sulfide signaling and imaging H2O2-dependent H2S production." Proc. Natl. Acad. Sci. USA 2013, 110, 7131. doi: 10.1073/pnas.1302193110 (Highlighted in the April 22 issue of Chemical & Engineering News)

    SF7-AM is now commercially available from Sigma-Aldrich!


Publications Unaffiliated with SMU:
  1. Michel, B. W.; Lippert, A. R.; Chang, C. J.* "A Reaction-Based Fluorescent Probe for Selective Imaging of Carbon Monoxide in Living Cells Using a Palladium- Mediated Carbonylation." J. Am. Chem. Soc. 2012 , 124, 15668.

  2. Lippert, A. R.; Van De Bittner, G. C.; Chang, C. J.* "Boronate Oxidation as a Bioorthogonal Reaction Approach for Studying the Chemistry of Hydrogen Peroxide in Living Systems." Acc. Chem. Res. 2011 , 47, 793.

  3. Lippert, A. R.; New, E. J.; Chang, C. J.* "Reaction-Based Fluorescent Probes for the Selective Imaging of Hydrogen Sulfide in Living Cells." J. Am. Chem. Soc. 2011 , 133, 10078. (Highlighted in the October 17 issue of Chemical & Engineering News)

  4. Lippert, A. R.; Keshari, K. R.; Kurhanewicz, J.; Chang, C. J.* "A Hydrogen Peroxide Responsive Hyperpolarized 13C MRI Contrast Agent." J. Am. Chem. Soc. 2011 , 133, 3776.

  5. Lippert, A. R.; Naganawa, A.; Keleshian, V. L.; Bode, J. W.* "Synthesis of Phototrappable Shapeshifting Molecules for Adaptive Guest Binding." J. Am. Chem. Soc. 2010 , 132, 15790.

  6. Lippert, A. R.; Gschneidtner, T.; Chang, C. J.* "Lanthanide-Based Luminescent Probes for Selective Time- Gated Detection of Hydrogen Peroxide in Water and Living Cells." Chem. Commun. 2010 , 46, 7510.

  7. Lippert, A. R.; Keleshian, V. L.; Bode, J. W.* "Dynamic Supramolecular Complexation by Shapeshifting Organic Molecules." Org. Biomol. Chem. 2009 , 7, 1529.

  8. Ju, L.; Lippert, A. R.; Bode, J. W.* "Stereoretentive Synthesis and Chemoselective Amide-Forming Ligations of C- Terminal Peptide alpha-Ketoacids." J. Am. Chem. Soc. 2008 , 130, 4253.

  9. Lippert, A. R.; Kaeobamrung, J.; Bode, J. W.* "Synthesis of Oligosubstituted Bullvalones: Shapeshifting Molecules Under Basic Conditions." J. Am. Chem. Soc. 2006 , 128, 14738.

  10. Khidekel, N.; Arndt, S.; Lamarre-Vincent, N.; Lippert, A.; Poulin-Kerstien, K. G.; Ramakrishnan, B.; Qasba, P. K.; Hsieh-Wilson, L. C.* "A Chemoenzymatic Approach toward Rapid and Sensitive Detection of O-GlcNAc Posttranslational Modifications." J. Am. Chem. Soc. 2003 , 125, 16162.